Research

Current publications relating to paediatric HIV can be found on the ISOSS and PENTA-ID websites.

Many research papers relating to paediatric HIV pre – 2021 are listed on the CHIPS website publications area.

Papers that may be of interest


Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial. Turkova, Anna et al. The Lancet. Child & adolescent health. 7 Aug. 2023


 Infant feeding: emerging concepts to prevent HIV transmission. Bamford A, Foster C, Lyall H et al. Curr Opin Infect Dis. Feb 2024. 


Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe. Malik F, Crichton S, Plotnikova Y et al. Pediatr Infect Dis J. 2024. 


 Beliefs about antiretroviral therapy and their association with adherence in young people living with perinatal HIV in England: a cross-sectional analysis.
White I, Judd A, Castro H et al. Adolescents and Adults Living with Perinatal HIV (AALPHI) Steering Committee. AIDS Care. 2024.


Psychological and Behavioural Within-participant Predictors of Adherence to Oral HIV Pre-Exposure Prophylaxis (PrEP).
Taylor A, Hayes R, Nwokolo N et alAIDS Behav. 2024. 


HIV-1 reservoir size after neonatal antiretroviral therapy and the potential to evaluate antiretroviral-therapy-free remission.
Persaud D, Bryson Y, Nelson BS, et al. Lancet HIV. Dec 2023.


Bone mineral density among children living with HIV failing first-line anti-retroviral therapy in Uganda: A sub-study of the CHAPAS-4 trial. Natukunda, Eva et al. PloS one vol. 18,7 e0288877. 20 Jul. 2023.


Incidence and severity of SARS-CoV-2 infection in children and young people with HIV in Europe. The European Pregnancy and Paediatric Infections Cohort Collaboration (EPPICC) study group. AIDS (London, England) vol. 37,10 (2023)


Neuropsychiatric manifestations and sleep disturbances with dolutegravir-based antiretroviral therapy versus standard of care in children and adolescents: a secondary analysis of the ODYSSEY trial. Turkova, Anna et al. The Lancet. Child & adolescent health. 7 Aug. 2023


Impact of the COVID-19 pandemic on the provision and uptake of services for the prevention of mother-to-child transmission of HIV in Zimbabwe. Chappell, Elizabeth et al. PLOS global public health. 14 Aug. 2023.


Population Pharmacokinetic Modeling of Dolutegravir to Optimize Pediatric Dosing in HIV-1-Infected Infants, Children, and Adolescents. Chandasana, Hardik et al. Clinical pharmacokinetics, 21 Aug. 2023.


Inadequate Lopinavir Concentrations With Modified 8-hourly Lopinavir/Ritonavir 4:1 Dosing During Rifampicin-based Tuberculosis Treatment in Children Living With HIV. Chabala, Chishala et al.The Pediatric infectious disease journal. 20 Jul. 2023.


Effective early antiretroviral therapy in perinatal-HIV infection reduces subsequent plasma inflammatory profile.  Nguyen, Athena N et al. Pediatric research 13 Jun. 2023


Sexual and reproductive health needs of young women living with perinatally acquired HIV. Nott, Veronica R et al. International journal of STD & AIDS. 6 Jun. 2023.


Does distribution of menstrual products through community-based, peer-led sexual and reproductive health services increase use of appropriate menstrual products? Findings from the Yathu Yathu trial. Hensen, Bernadette et al.  Reproductive health vol. 20,1 92. 20 Jun. 2023.


Predictors of participant retention in a community-based HIV prevention cohort: perspectives from the HPTN 071 (PopART) study. Bell-Mandla, Nomtha et al. Trials vol. 24,1 434. 27 Jun. 2023.


Slow and Steady But Not Related to HIV Stigma: Physical Activity in South Africans Living with HIV and Chronic Pain. Wadley, Antonia et al. AIDS and behavior vol. 27,6. 2023.


Infant postnatal prophylaxis following maternal viraemia during breastfeeding. Lees, Emily A et al. AIDS (London, England) vol. 37,7 (2023)


The hard part we often forget: providing care to children and adolescents with advanced HIV disease. Frigati, L.J et al. J Int AIDS Soc., 26: e26041 ( 2023) 


Effectiveness and safety of tenofovir alafenamide in children and adolescents living with HIV: a systematic review. O’Rourke, J et al. J Int AIDS Soc., 26: e26037. (2023)


Gestational diabetes in women living with HIV in the UK and Ireland: insights from population-based surveillance data. Bukasa, L.L et al.  J Int AIDS Soc., 26: e26078. (2023)


Screen: Unheard testimony. Talha Burki. The lancet. HIV vol. 9,12 (December 2022)


Effectiveness and safety of dolutegravir and raltegravir for treating children and adolescents living with HIV: a systematic review. Townsend, Claire L et al. Journal of the International AIDS Society vol. 25,11 (November 2022)


Does HIV knowledge change after involvement in a psychosocial programme for adolescents with HIV in Botswana? A one-year prospective cohort study. Evangeli M et al. Poster presented at International Workshop on HIV & Adolescence 2022 (October 2022)


Transition to independent care for youth living with HIV: a cluster randomised clinical trial. Njuguna, Irene N et al. The lancet. HIV vol. 9,12 (October 2022)


Learning and memory function in young people with and without perinatal HIV in England. Arenas-Pinto A et al. PloS one vol. 17,9 e0273645. (September 2022)


Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomised ODYSSEY trial. Amuge, Pauline et al. The lancet. HIV vol. 9,9 (September 2022)


Impact of SARS-CoV-2 pandemic on viral suppression for young adults living with perinatally acquired HIV infection. Hazell, George A et al. AIDS care, 1-6. (August 2022)


Antiretroviral choice and severe disease predict poorer neuropsychological outcomes in HIV+ children from Africa. Fairlie L et al. (August 2022)


Advancing the prevention and treatment of HIV in children: priorities for research and development. Penazzato, Martina et al. The lancet. HIV vol. 9,9 (July 2022)


Early neurodevelopment of HIV-exposed uninfected children in the era of antiretroviral therapy: a systematic review and meta-analysis. Wedderburn, Catherine J et al. The Lancet. Child & adolescent health vol. 6,6 (June 2022)


Sentebale Botswana, 2019-20 Evaluation report. Evangeli M et al. (March, 2022)

Do levels of mental health problems change after involvement in a psychosocial programme for adolescents with HIV in Botswana? A one-year prospective cohort study. Evangeli M et al. 


Trends in antiretroviral use in pregnancy in the UK and Ireland, 2008-2018. Rasi V et al. (Feburary, 2022)


The psychological impact of caring during the covid-19 pandemic on HIV nurses. Dr Hilary Piercy and Matthew Wills ( March, 2022)


Integration of mental health services into HIV healthcare facilities among Thai adolescents and young adults living with HIV. (2021) Sudjaritruk, T et al. 


Children living with HIV in Europe: do migrants have worse treatment outcomes? (2021) Chappell E et al


The Young People’s Survey. Evaluation of The Impact of The National Lockdown on young people with HIV and the CHIVA Support Services During The COVID-19 Pandemic in the UK. ( 2021) 


Factors associated with nonadherence to antiretroviral therapy among young people living with perinatally acquired HIV in England. (2020) Judd A et al.


Experiences of transition to adult care and readiness to self-manage care in young people with perinatal HIV in England. (2020) Sturgeon K et al.


Outcomes of second line antiretroviral therapy among children living with HIV: a global cohort analysis. (2020) Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Global Cohort Collaboration. 


Naming HIV to children:it’s time to talk Katie Rowson (2017)


Freedom to be: impact of CHIVA camp Irina Lut, Katie Rowson and Amanda Ely (2017)


Clinical status of adolescents with perinatal HIV at transfer to adult care in the UK/Ireland. Clinical Infectious Disease Collins, I. J., Foster, C., Tostevin, A., et al. (2017)