AALPHI Study

The AALPHI cohort study compared two groups of young people:

  • those who acquired HIV from birth
  • those who are HIV negative but either have a parent with HIV or live in the same household as a study participant who is living with HIV.

The focus of the study was on the impact of life-long HIV and long-term antiretroviral therapy (ART) on various areas of health, including cognitive function, psychosocial issues and sexual and reproductive health. Two face-to-face interviews took place over a five year period.

The study is now complete. Young people from Chiva worked on developing resources which report on the outcomes with the study team from the MCR Clinical Trials Unit at University College London.

You can learn about the study’s findings through the short film below.

Youth Trials Board

Chiva worked with Penta ID to deliver a UK Youth Trials Board (YTB) as part of a global programme enabling young people’s participation in clinical trials.

The Youth Trials Board (YTB) Project was a three-year pilot to develop a model of youth participation in paediatric HIV clinical trials. YTBs aim was to ensure young people’s meaningful and influential involvement in how clinical trials are designed, developed and delivered. The pilot engaged young people aged 15-21 years who were living with HIV in four countries, involving local organisations:

  • UK: Chiva 
  • Zimbabwe: Africaid Zvandiri and The University of Zimbabwe Clinical Research Centre (UZCRC)
  • South Africa: Enhancing Care Foundation, King Edward VII Hospital Clinical Trials Unit, Durban
  • Uganda: The Makerere University – John Hopkins University (MUJHU) Research Collaboration

Resources developed by the Youth Trials Board can be found at Penta ID.